Human umbilical vein graft

Human umbilical vein graft

A human umbilical vein graft (HUVG) is a specially prepared human umbilical vein that is used as a vascular graft. HUVGs have found use in arteriovenous fistulaeRubio PA, Farrell EM. Modified human umbilical vein graft arteriovenous fistulae as a source of angioaccess in maintenance hemodialysis. Cardiovasc Dis. 1980 Mar;7(1):51-57. PMID 15216281. [http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=15216281 Full Text] .] (for patients with ESRD undergoing hemodialysis), as an interposition graft between the subclavian artery and pulmonary artery (in the Blalock-Taussig shunt procedureLeao LE, Andrade JC, Succi JE, Cueva CC, Ribeiro EE, Carvalho AC, Buffolo E. Modified Blalock-Taussig shunt with an umbilical vein graft. Tex Heart Inst J. 1985 Mar;12(1):65-71. PMID 15227043. [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=341796 Full Text] .] ), and for peripheral bypass graft surgery, when the great saphenous vein (the preferred conduit) is unavailable or unusable.

HUVGs for peripheral bypass grafts are second only to the saphenous vein for long-term patency. [Neufang A, Espinola-Klein C, Dorweiler B, Reinstadler J, Pitton M, Savvidis S, Fischer R, Vahl C, Schmiedt W. Sequential femorodistal composite bypass with second generation glutaraldehyde stabilized human umbilical vein (HUV). Eur J Vasc Endovasc Surg. 2005 Aug;30(2):176-83. PMID 15950502.] However, they do have some tendency to form aneurysms and require more delicate handling than synthetic graft material from PETE (Dacron) or PTFE.

References

External links

* [http://www.braile.com.br/INGLES/veiaumbili.htm Umbilical vein graft] - a picture, specifications and uses. Braile Biomedica.


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