Poly ICLC

Poly ICLC

Drugbox
IUPAC_name =


CAS_number =
ATC_prefix = L03
ATC_suffix = AX08
PubChem =
DrugBank =
chemical_formula =
molecular_weight =
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
legal_status =
routes_of_administration =

Poly ICLC is an immunostimulant.

It consists of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA. [cite web |url=http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=39559 |title=Definition of poly ICLC - National Cancer Institute Drug Dictionary |accessdate=2007-11-13 |format= |work=]

It is a ligand for toll like receptor-3.cite journal |author=Zhu X, Nishimura F, Sasaki K, "et al" |title=Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models |journal=Journal of translational medicine |volume=5 |issue= |pages=10 |year=2007 |pmid=17295916 |doi=10.1186/1479-5876-5-10]

References

http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=39559


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • poly-ICLC — A substance that is being studied in the treatment of cancer and for its ability to stimulate the immune system. It is made in the laboratory by combining the nucleic acid RNA with the chemicals poly L lysine and carboxymethyl cellulose …   English dictionary of cancer terms

  • Nventa Biopharmaceuticals Corporation — Nventa Biopharmaceuticals Former type Public (TSX: NVN) Industry B …   Wikipedia

  • HspE7 — is an investigational therapeutic vaccine candidate being developed by Nventa Biopharmaceuticals for the treatment of precancerous and cancerous lesions caused by the human papillomavirus (HPV). HspE7 uses recombinant DNA technology to covalently …   Wikipedia

  • ATC code L03 — A section of the Anatomical Therapeutic Chemical Classification System.L Antineoplastic and immunomodulating agentsL03A Cytokines and immunomodulatorsL03AA Colony stimulating factors:L03AA02 Filgrastim:L03AA03 Molgramostim:L03AA09… …   Wikipedia

  • Código ATC L — Anexo:Código ATC L Saltar a navegación, búsqueda El código ATC o Sistema de Clasificación Anatómica, Terapéutica, Química (ATC: acrónimo de Anatomical, Therapeutic, Chemical classification system) es un índice de sustancias farmacológicas y… …   Wikipedia Español

  • Anexo:Código ATC L — El código ATC o Sistema de Clasificación Anatómica, Terapéutica, Química (ATC: acrónimo de Anatomical, Therapeutic, Chemical classification system) es un índice de sustancias farmacológicas y medicamentos, organizados según grupos terapéuticos.… …   Wikipedia Español

  • Granulocyte colony-stimulating factor — Not to be confused with granulocyte macrophage colony stimulating factor. Colony stimulating factor 3 (granulocyte) Crystal structure of 3 molecules of human G CSF. From PDB …   Wikipedia

  • Filgrastim — Not to be confused with granulocyte macrophage colony stimulating factor. Filgrastim Systematic (IUPAC) name Human granulocyte colony stimulating factor Clinical dat …   Wikipedia

  • List of oncology-related terms — This is a list of terms related to oncology. The original source for this list was the U.S. National Cancer Institute s public domain Dictionary of Cancer Terms . NOTOC 1 * 10 propargyl 10 deazaaminopterin * 12 O tetradecanoylphorbol 13 acetate * …   Wikipedia

  • Pegfilgrastim — Systematic (IUPAC) name N (3 Hydroxypropyl)Methionylcolony stimulating Factor (human), 1 Ether with .Alpha. Methyl .Omega. Hydroxypoly(Oxyethylene) Clinical data Trade names Neulasta AHFS/Drugs.com …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”