Ethylamphetamine

Ethylamphetamine
Ethylamphetamine
Systematic (IUPAC) name
N-ethyl-1-phenyl-propan-2-amine
Clinical data
Pregnancy cat.  ?
Legal status Schedule 1
Routes Oral, Sublingual, Insufflated (Snorted), Inhaled (Vaporized), Intravenous, Rectal
Pharmacokinetic data
Metabolism Hepatic
Excretion Renal
Identifiers
CAS number 457-87-4
ATC code A08AA06
PubChem CID 9982
ChemSpider 9588 YesY
KEGG D07114 YesY
ChEMBL CHEMBL276443 YesY
Chemical data
Formula C11H17N 
Mol. mass 163.259 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Ethylamphetamine (Apetinil, Adiparthrol), also known as etilamfetamine or N-ethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes. It was invented in the early 1900s and was subsequently used as an anorectic or appetite suppressant in the 1950s,[1] but was not as commonly used as other amphetamines such as amphetamine, methamphetamine, and benzphetamine, and was largely discontinued once newer drugs such as phenmetrazine were introduced.

Contents

Chemistry

The molecular structure of ethylamphetamine is analogous to amphetamine's.[Note 1] It is a substituted amphetamine, with an ethyl group on the amphetamine backbone.[Note 2][Note 3]

Recreational use

Ethylamphetamine can be used as a recreational drug and, while its prevalence is less than amphetamine's, it is still encountered as a substance taken for recreational purposes.

Ethylamphetamine produces effects similar to amphetamine and methamphetamine, its potency being slightly greater than amphetamine's and lesser than methamphetamine's.[Note 4]

See also

References

  1. ^ Junet, R. (1956). "Ethylamphetamine in the treatment of obesity". Praxis 45 (43): 986–988. PMID 13389142.  edit

Notes

  1. ^ Amphetamine is a substituted phenethylamine with a methyl group at RA position.
  2. ^ The ethyl group of ethylamphetamine is at RN position, hence the name N-ethylamphetamine.
  3. ^ Ethylamphetamine is structurally similar to N-methylamphetamine (methamphetamine), the ethyl group being replaced in methamphetamine with a methyl group.
  4. ^ Ethylamphetamine's higher potency may make its risk of causing abuse, dependence and/or addiction greater compared to amphetamine.

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